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Physicians discover a protein that reprogrammes connective tissue cells February 1, 2019 The increased deposition of connective tissue is a problem in chronic diseases of many organs such as the lungs (idiopathic pulmonary fibrosis), liver (cirrhosis), kidneys (kidney fibrosis), gut (graft versus... Continue

Network supplies bones and helps immune cells to quickly reach the sources of inflammation January 25, 2019 A network of very fine blood vessels that connects bone marrow directly with the blood supply of the periosteum that was previously overlooked has now been discovered by Dr. Anika Grüneboom... Continue

A new article from the CRC 1181: Inflammation was recently published in Nature Communications, elaborating on aspects leading to the resolution of inflammation, what happens if this goes wrong and what this has in common with chronic inflammatory diseases. Continue

Gambling until the doctor arrives: Now the strategy game "Game In Flame - Battle Against Inflammation" has been expanded to include a module on rheumatoid arthritis after gout, intestinal inflammation and asthma. The player controls a fatal quartet consisting of macrophages, T-cells, B-cells and the messenger TNF with the targeted use of drugs. Continue

Inflammation needs energy. This is not least generated from oxygen, which is essential for the cells of the immune system. On the one hand, oxygen is an essential element for the survival of cells, but on the other hand it also functions as a "fuel" for the fire of inflammation. Continue

Erlangen Scientists decipher how dangerous inflammations develop after stem cell transplantation Continue

It is well known that healthy eating increases our general sense of wellbeing. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now discovered that a fibre-rich diet can have a positive influence on chronic inflammatory joint diseases, leading to stronger bones. The researchers have published their findings in the renowned journal Nature Communications. Continue

How does the immune system decide which cells are good and which are evil? This distinction is of central importance, because some belong to their own organism, while others must be attacked and disposed of. Prof. Dr. Gerhard Krönke made an important contribution to this area. Continue

The oldest defense battle on earth? This has nothing to do with Germanic heroes or Roman legions, but with the battle of the immune system against invading pathogens - for example, in chronic inflammatory diseases such as Gout, Asthma, Crohn's Disease or Ulcerative Colitis. The educational game "Gam... Continue

Stomach cancer is one of the five most deadly types of cancer: according to statistics from the World Health Organization (WHO), about 750,000 patients die of this disease every year. The main trigger is the bacterium Helicobacter pylori (H. pylori). There are currently no effective therapies for ga... Continue