Preclinical Imaging Center Erlangen (PIPE)

The PIPE is a central unit within the CRC 1181 which offers preclinical investigations of  high resolution in vivo imaging. PIPE was integrated into the CRC1181 to obtain detailed vital imaging of the inflammatory process,   disease progression and  resolution of inflammation with a focus on translating our results to clinical practice.

Technics and methods

Modalities Magentic Resonance Tomography (MRI) Positronen Emissions Tomography (PET CT)/ Single Photon
Emission Computed Tomography (SPECT)/ Computed Tomography (CT)
Bild3 Bild4
  • high resolution imaging
  • Mapping relaxation time (T1, T2, T2*)
  • Dynamic contrast extension MRI
  • diffusion-weighted imaging situation
  • high resolution imaging
  • Quantitative tracer accumulation (fluorodeoxyglucose, fluoride and others)
  • Tracer kinetics
Data display (inflammation)
  • Qualitative and quantitative analysis of microstructures
  • Vascularization (z.B. blood volume, vascular permeability)
  • Diffusion characteristic
  • Qualitative und quantitative analyzis of microstructures
  • Inflammation activity or tissue activity
  • Metabolism
Resolution macro macro