Inflammation is a part of an elaborate human defence system. This process needs a functioning immune system to allow the defence against dangers such as mechanical, chemical and biological signals or at least to contain and therefore prevent organ damage. The human body responds rapidly to dangers by an inflammatory response, which is also rapidly resolved after the dangers have been removed allowing for tissue repair to begin. How resolution of inflammation functions is still inadequately researched and will thus be researched by the CRC1181.

The Collaborative Research Centre (CRC) 1181 titled Checkpoints for Resolution of Inflammation is funded by the German Research Council (DFG) since July, 1st, 2015 and was established to investigate the molecular mechanisms involved in the resolution of inflammation. Our main focus is on why resolution of inflammation fails in chronic inflammatory diseases such as arthritis, Crohn’s disease and asthma which are characterized by chronic inflammation of the inner surfaces of the body, usually having serious health implications for its patients.

In the 2nd CRC 1181 Minisymposium special fields of inflammation research will be highlighted. This event focuses on different mechanisms which are responsible for pathogenesis and resolution of inflammatory bowel diseases.

World Arthritis Day (WAD) is a global initiative bringing people together to raise awareness of issues affecting people with RMDs. WAD is organized every year on 12th October and is supported by a year-round global campaign.



  • Organization: Universitätsklinikum Erlangen
  • Working group: Department of Internal Medicine 3
  • Address:
    Ulmenweg 18
    91054 Erlangen

CRC1181 Social

Game In Flame - Trailer 1